| Campo Dublin Core | Valor | Língua |
|---|
| dc.contributor.advisor | Carvalho, Juliana Lott de | - |
| dc.contributor.author | Maia, Ariel Moura | - |
| dc.identifier.citation | MAIA, Ariel Moura. In vitro models of diabetes: review and critical analysis. 2019. 28 f. Trabalho de Conclusão de Curso (Bacharelado em Farmácia)—Universidade de Brasília, Brasília, 2019. | pt_BR |
| dc.description | Trabalho de Conclusão de Curso (graduação)—Universidade de Brasília, 2019. | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.subject.keyword | Diabetes | pt_BR |
| dc.title | In vitro models of diabetes : review and critical analysis | pt_BR |
| dc.type | Trabalho de Conclusão de Curso - Graduação - Bacharelado | pt_BR |
| dc.date.accessioned | 2021-09-06T17:30:52Z | - |
| dc.date.available | 2021-09-06T17:30:52Z | - |
| dc.date.submitted | 2019 | - |
| dc.identifier.uri | https://bdm.unb.br/handle/10483/28459 | - |
| dc.language.iso | Inglês | pt_BR |
| dc.rights.license | A concessão da licença deste item refere-se ao termo de autorização impresso assinado pelo autor que autoriza a Biblioteca Digital da Produção Intelectual Discente da Universidade de Brasília (BDM) a disponibilizar o trabalho de conclusão de curso por meio do sítio bdm.unb.br, com as seguintes condições: disponível sob Licença Creative Commons 4.0 International, que permite copiar, distribuir e transmitir o trabalho, desde que seja citado o autor e licenciante. Não permite o uso para fins comerciais nem a adaptação desta. | pt_BR |
| dc.contributor.advisorco | Araújo, Felipe Saldanha de | - |
| dc.description.abstract1 | Diabetes mellitus (DM) is a metabolic disease, and its prevalence has increased over the
last decades, affecting more than 8.6% of the world population. Despite extensive
research, the mechanism of diabetes development and its complications are still not fully
understood. The present review was designed to describe in vitro methods used to study
diabetes mellitus, with a critical analysis of their advantages and limitations. We searched
Pubmed database for free full-text articles that were published between 2014 and 2019
that contained “diabetes mellitus” and “in vitro” in their content and restricted the result to
human studies using the species filter. Clinical reports were excluded. The search and
filtering of articles rendered 927 results, of which 25 were used in this review. The majority
of studies used glucose modulation models, even though primary cells and serum derived
from DM patients were also used, in addition to varied strategies focused on mimicking
isolated aspects of the disease. Therefore, different model systems are available for the
study of diabetes mellitus in vitro, each with its own set of advantages and limitations. The present review will provide relevant information, which may support the appropriate choice
of experimental models in the field. | pt_BR |
| Aparece na Coleção: | Farmácia - Campus Darcy Ribeiro
|
